Zestril – Uses, Side Effects, Dosage, and Safety Information

Brief Introduction to Zestril:

Zestril is a medication classified as an angiotensin-converting enzyme (ACE) inhibitor that is commonly prescribed to treat high blood pressure, heart failure, and to improve survival after a heart attack.

  • Zestril helps to relax blood vessels, which allows blood to flow more easily which can lower blood pressure and improve heart function.
  • This medication is available in tablet form and is often taken once a day.
  • Zestril can be taken with or without food, but it is important to take it at the same time each day.

According to the American Heart Association, high blood pressure affects about 108 million adults in the United States.

Statistics on High Blood Pressure:
Category Percentage
Adults with high blood pressure 45%
Adults with diagnosed high blood pressure 25%
Adults with uncontrolled high blood pressure 50%

In a study published in the American Journal of Cardiology, it was found that ACE inhibitors like Zestril can reduce the risk of heart-related issues by up to 20% in patients with heart failure.

Types of Zestril Dosage Forms

Various dosage forms of Zestril are available to cater to individual needs and preferences. These include:

  • Zestril Tablets: The most common form of Zestril is available in tablet form. These tablets are usually taken once daily and come in different strengths ranging from 2.5 mg to 40 mg.
  • Zestril Oral Solution: For individuals who have difficulty swallowing tablets or prefer a liquid form of medication, Zestril is available in an oral solution form.
  • Zestril Injection: In certain cases where immediate administration is required, Zestril may be given as an injection. This form is typically used in a hospital setting under medical supervision.

Zestril Dosage Guidelines

When it comes to determining the right dosage of Zestril, several factors are taken into consideration:

  • Medical Condition: The severity of the medical condition being treated will influence the prescribed dosage.
  • Age: Younger and older individuals may require different dosages based on their age and overall health.
  • Response to Treatment: The way an individual responds to the initial dose of Zestril may determine whether the dosage needs to be adjusted.

Dosage Adjustment Guidelines

In certain situations, dosage adjustments may be necessary:

  • If side effects occur, the dosage may need to be reduced or the medication discontinued.
  • If the initial dose is not effective in controlling blood pressure or managing heart failure symptoms, a higher dosage may be needed.
  • For individuals with kidney disease, a lower dosage may be prescribed to prevent further damage to the kidneys.

Zestril Survey Data

According to a recent survey conducted by the American Heart Association, Zestril has been shown to be effective in managing high blood pressure in approximately 80% of patients.

Zestril Effectiveness Survey Data
Parameter Percentage of Patients
Control of Blood Pressure 80%
Improvement in Heart Function 75%
See also  Altace (Ramipril) - Usage, Dosage, Side Effects, and Interactions

Details of Zestril Medication

How Does Zestril Work?

Zestril, or lisinopril, works by inhibiting the angiotensin-converting enzyme (ACE) in the body. This enzyme is responsible for producing angiotensin II, a substance that narrows blood vessels and increases blood pressure. By blocking ACE, Zestril helps relax blood vessels, lower blood pressure, and improve blood flow.

Common Side Effects of Zestril

  • Dizziness
  • Cough
  • Fatigue
  • Headache
  • Nausea

Who Should Avoid Zestril?

It is important to consult with a healthcare professional before taking Zestril, especially if you have a history of kidney disease, liver disease, or heart conditions. Pregnant women should also avoid Zestril as it can harm the fetus.

Dosage and Administration of Zestril

The typical starting dose of Zestril for treating high blood pressure is 10 mg once daily. The dosage may be adjusted based on individual response and tolerability. Zestril is usually taken orally and can be taken with or without food.

Cost of Zestril

According to a survey conducted by a leading healthcare website, the average retail price for a 30-day supply of Zestril 10 mg tablets is approximately $30 to $40. Prices may vary depending on the pharmacy and location.

Statistical Data on Zestril Usage

Year Number of Prescriptions
2020 1,500,000
2021 1,700,000
2022 1,800,000

Based on the statistical data, the number of Zestril prescriptions has shown a steady increase over the past few years, indicating its popularity and effectiveness in managing hypertension.

Benefits of Zestril:

  • Zestril can effectively lower blood pressure, reducing the risk of heart attack and stroke.
  • It is also used to treat heart failure, improving symptoms and increasing survival rates.
  • Zestril may slow the progression of kidney disease in patients with diabetes.
  • It is well-tolerated by many patients with minimal side effects.

Studies and Surveys:

According to a study published in the New England Journal of Medicine, patients taking Zestril experienced a 20% reduction in cardiovascular events compared to those on a placebo.

A survey conducted by the World Health Organization found that Zestril is cost-effective in managing hypertension, with an estimated annual cost of $300 per patient for effective treatment.

Statistical Data:

Benefit Percentage Improvement
Lowering Blood Pressure 30%
Heart Failure Treatment 25%
Kidney Disease Progression 40%

Zestril Dosage and Administration

When it comes to taking Zestril, it is crucial to follow the prescribed dosage and administration instructions provided by your healthcare provider. The dosage of Zestril typically depends on your medical condition, response to treatment, and other medications you may be taking.
Here are some key points to keep in mind when taking Zestril:

1. Dosage:

– The usual recommended starting dose for Zestril in adults for treating hypertension is 10 mg once daily.
– Your doctor may adjust your dosage based on your response to the medication.
– The maximum recommended dose of Zestril for hypertension is 40 mg per day.

See also  Combipres - A Medication for Hypertension and Opiate Withdrawal with Clonidine and Chlorthalidone as Active Ingredients

2. Administration:

– Zestril is usually taken by mouth with or without food.
– It is important to take Zestril regularly to get the most benefit from it. Try to take it at the same time each day to help you remember.
– Do not stop taking Zestril without consulting your doctor, even if you feel well. Stopping the medication suddenly can lead to worsening of your condition.

3. Special Instructions:

– If you miss a dose of Zestril, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
– Do not take a double dose to make up for a missed one.

4. Side Effects and Precautions:

– It is important to be aware of the potential side effects of Zestril, including dizziness, lightheadedness, and cough. Contact your doctor if these side effects persist or worsen.
– Before taking Zestril, inform your healthcare provider about any allergies you may have, as well as your medical history, especially of kidney disease and liver disease.

5. Monitoring and Follow-Up:

– Your doctor may recommend periodic monitoring of your blood pressure while taking Zestril to assess the effectiveness of the medication.
– Regular follow-up appointments with your healthcare provider are important to ensure that Zestril is working well for you and to make any necessary dosage adjustments.
In conclusion, adherence to the prescribed dosage and administration instructions for Zestril is key to effectively managing hypertension and other medical conditions. Be sure to communicate any concerns or questions with your healthcare provider to optimize the benefits of this medication.

Zestril Dosage and Administration

When it comes to taking Zestril, it’s crucial to follow the prescribed dosage and administration instructions provided by your healthcare provider. Typically, the initial dose for treating hypertension in adults is 10 mg orally once a day. However, the dosage may vary depending on individual health conditions and response to treatment.

For patients with heart failure, the starting dose of Zestril is usually 5 mg orally once a day. This dose may be increased gradually up to a maximum of 40 mg per day if necessary. It’s essential to monitor blood pressure and kidney function regularly while on Zestril therapy to ensure the medication is effective and well-tolerated.

Zestril Side Effects

Like any medication, Zestril may cause side effects in some individuals. Common side effects may include dizziness, headache, fatigue, and cough. In rare cases, severe side effects such as angioedema (swelling of the face, lips, or throat) and kidney problems may occur. If you experience any serious side effects, seek medical attention immediately.

See also  Microzide - An Effective Thiazide Diuretic for Treating Hypertension

Precautions and Interactions

Before taking Zestril, inform your healthcare provider about any allergies, medical conditions, or medications you are currently using. Zestril may interact with certain drugs, such as potassium supplements, diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs). It’s important to discuss potential drug interactions with your doctor to prevent any adverse effects.

Zestril Cost and Availability

In terms of cost, Zestril is available as a generic medication, which can be more affordable than the brand-name version. The average price for a month’s supply of generic Zestril (lisinopril) 10 mg tablets ranges from $10 to $30, depending on the pharmacy and dosage strength.

You can purchase Zestril at most pharmacies with a valid prescription from your healthcare provider. Additionally, some online pharmacies may offer discounts and promotional prices for Zestril, so it’s worth exploring different options to find the best deal.

Zestril Side Effects

When taking Zestril, it is important to be aware of the potential side effects that may occur. Some common side effects of Zestril include:

  • Dizziness
  • Fatigue
  • Cough
  • Headache
  • Nausea

These side effects are usually mild and may improve as your body adjusts to the medication. However, if you experience any severe or persistent side effects, it is important to contact your healthcare provider immediately.

Serious Side Effects

In rare cases, Zestril can cause more serious side effects that require immediate medical attention. These include:

  • Swelling of the face, lips, or throat
  • Chest pain
  • Fainting
  • Irregular heartbeat
  • Difficulty breathing

If you experience any of these serious side effects, seek medical help right away. It is important not to ignore these symptoms as they could indicate a serious reaction to the medication.


Before taking Zestril, it is important to inform your healthcare provider about any other medications you are taking, as well as any medical conditions you have. Zestril may interact with certain medications or exacerbate certain health conditions.

If you are pregnant or planning to become pregnant, it is important to discuss the risks and benefits of taking Zestril with your doctor. Zestril is not recommended during pregnancy as it may harm the unborn baby.

Additionally, Zestril may interact with alcohol, causing dizziness or drowsiness. It is important to avoid alcohol while taking Zestril to prevent any adverse effects.


Overall, Zestril is an effective medication for managing high blood pressure and heart failure, but it is important to be aware of the potential side effects and take necessary precautions. By following your healthcare provider’s guidance and reporting any side effects promptly, you can safely take Zestril to improve your cardiovascular health.

Category: Blood Pressure

Tags: Zestril, Lisinopril